Gilles discovered HNF-1 in 1985 while a post doctoral fellow in the laboratory and showed that it regulated a wide group of genes expressed in endodermal cells. He was an Investigator at the Pasteur Institute. gmcourt@pasteur.fr.and just recently moved to The Weizmann Institute of Science, 76100 Rehovot, Israel. See the August 2003 issue of Nature […]
Susan Baumheuter cloned HNF-1a and HNF-1b while in the lab. Susan helped set up the west coast branch of Celera at a time when it was just starting. Recently she decided to take off some time and raise her children. She can be reached at: sbaumneuter@msn.com.
Paul Utz: worked in the lab as a medical student and named NF-AT transcription complexes. For those of you that hate the name, he is entirely to blame. After a short time as an Assistant Professor at Harvard he joined the faculty at Stanford University and is now working on autoimmunity. Pjutz@leland.stanford.edu
Jeng Peng Shaw with David Durand and Paul Utz identified NF-AT as a regulator of early activation genes in T cells that coordinate the immune response. J-P is now a Scientist at Advanced Medicine, Inc. in South San Francisco.
Jay Toole worked in the lab during the time he was a medical student at Stanford after cloning Factor VIII at Genetics Institute. He is presently director of clinical research at Gilead.
Katie was a graduate student in the laboratory and defined the regions of the IL-2 promoter essential for its activity. She purifed jun D as a regulator of IL-2 (Ullman Science 1990) and is now an Assistant Professor at the University of Utah where she is studying the mechanisms underlying nuclear import and export. .Katie […]
Dirk Mendel discovered and cloned DCoH as a cofactor for the actions of HNF-1a and HNF-1b (Science 1991). He is now Associate Director for pre-clinical therapeutics at Sugen in South San Francisco. He can be reached at dirk-mendel@sugen.com.
Beth came to our laboratory as a technician from UC Santa Cruz and while in the lab discovered with David Durand that NF-AT was a specific target of cyclosporin and FK506 (Emmel et al Science 1989). She went from our lab to Vet School and is now a practicing vet specializing in small animals on […]
Andrew Serafini was a shared graduate student with the Hertzenberg lab. He isolated somatic cell mutations that are not able to activate the cellular CRAC channels and hence demonstrated with Rich Lewis in the Department of Molecular and Cellular Physiology that the CRAC channel was essential for lymphocyte activation and NFAT transcriptional competence. Andrew decided […]
Steve Fiering was really a Hertzenberg lab graduate student that spent a lot of time in the lab and with Cor Verwei developed the NF-AT LacZ system now commonly used for measuring transcriptional activity in individual cells. He used this technique to show that genes seemed to be in an “off” or “on” state and […]