Gilles discovered HNF-1 in 1985 while a post doctoral fellow in the laboratory and showed that it regulated a wide group of genes expressed in endodermal cells. He was an Investigator at the Pasteur Institute. gmcourt@pasteur.fr.and just recently moved to The Weizmann Institute of Science, 76100 Rehovot, Israel. See the August 2003 issue of Nature for a recent paper by Gilles group.