Chan worked with Neil Clipstone to define the mechanism of nuclear export of the NF-ATc1 protein by first defining mutations that prevented nuclear export and then purifying the kinases that specifically phosphorylate these sites. He found that GSK3 phosphorylates the specific sites after a still unidentified kinase primed the protein for later phosphorylation by GSK3. Chan returned to his home state of Washington where he now works for ICOS and can be reached at cbeals@icos.com