Hank made alleles of genes that can be rapidly and reversibly regulated with small molecules. He built alleles of Pax6 and GSK3b and made mice by homologous recombination that allow regulated degradation of these proteins. Perhaps most exciting are mice having alleles of FKBP12 that have a nuclear export sequence knocked into them allowing rapid export of proteins from the nucleus. These mice should allow an unprecedented level of control over the function of any nuclear protein. Hank contributed to many other studies in the lab including the design of new classes of macrolide based small molecule regulators and joined the faculty at Baylor University in the fall of 2006. He can be reached at: bayle@bcm.tmc.edu.