Ollie Rando
Ollie was an MD/PhD student in the lab. He discovered that the mammalian SWI/SNF-Like BAF complex binds PIP2 and accelerates the rate of actin filament formation. He also studied the genomic transcriptional response to co-stimulation of T lymphocytes and demonstrated that CD28 induces quantitative rather than qualitative changes in gene activation. His work also lead to the realization that PI3 kinase regulated NFAT signaling by inhibiting nuclear GSK3 and preventing nuclear export of the NFATc proteins. He joined the Harvard Fellows program at the Institute for Chemical Biology and now has his own group at the University of Mass. For some of his recent publications see: Cell. 2008 Nov 28;135(5):789-91 and Science. 2007 Mar 9;315(5817):1405-8.