Shi-Chu investigated the role of calineurin-NFAT signaling in the development of the neural crest. She found that calcineurin is essential for the production of myleinating Schwann cells. It appears to assume specificity in the Schwann cells by cooperating with Sox10 and controlling genes such as Krox20, which in turn directly controls the myelination genes.. This data was published in Science in Jan 2009. She recently became a research scientist at Tacere Therapeutics and can be reached at sckao1@gmail.com