Past Lab Members

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Ollie Rando

Ollie Rando

Ollie was an MD/PhD student in the lab. He discovered that the mammalian SWI/SNF-Like BAF complex binds PIP2 and accelerates the rate of actin filament formation. He also studied the genomic transcriptional response to co-stimulation of T lymphocytes and demonstrated that CD28 induces quantitative rather than qualitative changes in gene activation. His work also lead […]

Oli Bell

Oli Bell

Oli Bell and Nate Hathaway developed an approach to effectively study chromatin dynamics in living cells.   The approach involves using small molecule inducers of proximity to add or quickly remove different chromatin regulatory activities to one allele of a single gene in living cells or even a  living mouse.  His work showed that one […]

Keji Zhao

Keji Zhao

Keji is now a Senior Investigator at the Laboratory of Molecular Immunology at the NIH. He discovered that the mammalian SWI/SNF-like BAF complex contains b-actin as well as an actin-like protein and that actin plays a role in regulating the ATPase activity of the chromatin remodeling complex. One of his recent paper can be found […]

Chris Weber

Chris Weber

Chris discovered that BAF complexes repress the hox genes in ES cells by a remarkable mechanism in which the complexes evict polycomb at many sites over the genome allowing it to rapidly accumulate and repress the hox genes.